Excitatory Muscarinic Modulation Strengthens Virtual Nicotinic Synapses on Sympathetic Neurons and Thereby Enhances Synaptic Gain
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چکیده
منابع مشابه
Excitatory muscarinic modulation strengthens virtual nicotinic synapses on sympathetic neurons and thereby enhances synaptic gain.
Acetylcholine excites many neuronal types by binding to postsynaptic m1-muscarinic receptors that signal to ion channels through the G(q/11) protein. To investigate the functional significance of this metabotropic pathway in sympathetic ganglia, we studied how muscarinic excitation modulated the integration of virtual nicotinic excitatory postsynaptic potentials (EPSPs) created in dissociated b...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2006
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00589.2006